This medicine can let you feel depressed!

The medical regulator is reopening an inquiry into Roaccutane-a medicine used to cure acne.

According to an international news website, the case is going to be reopened after teen suicides were linked to its prescriptions this year.

Roaccutane or Accutane is usually suggested by dermatologists to cure severe acne. However, it has been connected to depression and suicide. The main ingredient in the medicine is Isotretinoin. The connection between Isotretinoin and depression and suicide is familiar but is debatable.

According to the information provided from the Medicine and Healthcare products Regulatory Agency (MHRA), over twelve deaths were reported in 2019. Out of these, 10 by suicide by people who were recommended to take Roaccutane.

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MHRA had opened reopened the inquiry.

The users of this medicine are advised by MHRA to consult immediately to the doctor if they feel depressed or have suicidal thoughts after consuming Roaccutane.

Given that Reoccutane is also suggested to treat acne in Pakistan.

According to a research published in Current Therapeutic Research of 2019, the medicine is said to introduce depression and related attitudes by lessening “adult neurogenesis or altering expression of components of the serotonergic neurotransmitter system, resulting in impaired serotonin signaling,”

Given that Isotretinoin is an oral medicine suggested for acne. It works by removing oily sebum production that causes acne. It is made up of 13-cis-retinoic acid that is a type of vitamin A. However, abnormal levels of retinoids can affect brain functioning, especially the impact on cognition on the brain.