Alzheimer’s disease-What research says about its cause?

Alzheimer’s disease is related to the dementia-mental issue that is linked with memory, thinking ability and behavior. Alzheimer’s disease makes up over 60 to 80 percent of dementia. It influences gradually but creates the worst impacts on the daily routine.

Alzheimer’s disease occurs mostly in people of old age. However, people under the age of 65 also face this disorder, depending on various factors such as trauma, disturb nutrition and so on. Millions of people around the globe grab Alzheimer’s disease.

Visible symptoms include changes in cognition, memory loss, difficulty remembering newly-memorized information, confusion, and other related activities. The symptoms will be visible gradually with time.

Researchers claim that Alzheimer’s disease is caused due to the accumulation of beta-amyloid in the brain. They claim that beta-amyloid disturbs the interaction between the brain and the cells. However, there are other reasons as well.

New research conducted in the University Of California San Diego School Of Medicine and Veterans Affairs says that beta-amyloid will not lead directly to the disorder.

The research was published in the journal Neurology. The author Prof. Mark Bondi said, “the scientific community has long thought that amyloid drives the neurodegeneration and cognitive impairment associated with Alzheimer’s disease,”

Over 747 participants worked in the research and the researchers tested their different levels of cognitive health.

Over 305 participants were cognitively healthy, 289 had mild cognitive impairment and 153 had Objectively-defined subtle cognitive difficulties or OBJ-SCD.

Hydration levels and cognition in adults

Prof. Bondi and the team found in the research that beta-amyloid that make a rate faster with obj-SCD than those who were declared healthy. People with obj-SCD had thinning of brain matter in the place named entorhinal cortex.

Entorhinal cortex, which handles memory function of the brain, decrease in volume and lead to Alzheimer’s disease.

The study suggested that the decreasing of the Entorhinal cortex cause the disorder, as participants with mild impairment contained beta-amyloid and it was not growing so fast.

While several types of research are being conducted to exactly examine the problem and identify cures, there is still a need to solve the issue from the roots.