Guinness: 54-atom molecular knot record. Tighter Knot: Metallaknot beats 2020 with BCR 18. Molecular Milestone: Advances material science. In a groundbreaking achievement, researchers have secured a place in the Guinness Book of World Records by creating the smallest and tightest knot ever known at the molecular scale. The team, as reported by Gizmodo, crafted a trefoil-shaped knot composed of 54